O sinergismo entre a desnutrição protéico-calórica e a leishmaniose visceral
Resumo
A desnutrição protéico-calórica e a leishmaniose visceral constituem importantes problemas de saúde pública que afetam milhões de pessoas no mundo todo. Atualmente tem sido amplamente aceito que a imunidade ou a susceptibilidade a doenças infecto-parasitárias estão diretamente relacionadas com o estado nutricional do hospedeiro. Contudo, os mecanismos que regem a relação desnutrição protéico-calórica e o curso da leishmaniose visceral são múltiplos e pouco esclarecidos. Neste sentido, este estudo tem como objetivo apresentar através de uma revisão crítica da literatura, os aspectos mais importantes sobre a relação entre estas duas enfermidades. Para isso foram identificados e analisados 77 trabalhos publicados entre os anos de 1960 e 2007, utilizando-se como principais fontes os bancos de dados LILACS-BIREME e MEDLINE. Tanto a desnutrição protéicocalórica quanto a infecção causada por parasitos do gênero Leishmania são problemas freqüentes nos dias atuais e, na medida em que novos estudos são desenvolvidos sobre o tema, torna-se imprescindível que a sociedade os conheçam.
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