Determinantes sociais e biológicos da ocorrência de câncer de próstata em indivíduos atendidos no hospital naval de Salvador

Amanda Pires Arruda Pereira da Silva; Viviane Vitória dos Santos; Jerusa da Mota Santana; Kim Jurgen Erfani; Sibele de Oliveira Tozetto Klein

doi:10.22481/rsc.v20i2.13541

Autores/as

Amanda Pires Arruda Pereira da Silva Português https://orcid.org/0000-0001-7284-7145
Viviane Vitória dos Santos Hospital Naval de Salvador https://orcid.org/0000-0003-4246-4447
Jerusa da Mota Santana Universidade Federal do Recôncavo da Bahia https://orcid.org/0000-0002-8920-0097
Kim Jurgen Erfani Português https://orcid.org/0009-0007-3463-6188
Sibele de Oliveira Tozetto Klein Universidade Federal do Recôncavo da Bahia https://orcid.org/0000-0002-3456-9663

DOI:

https://doi.org/10.22481/rsc.v20i2.13541

Palabras clave:

Prostatic Neoplasms, Lipids, Health Profile

Resumen

Occurrence of prostate cancer is associated with ethnic and biological factors. There are studies that do not consider the lipid profile as a biomarker and disagree that inequalities and ethnic/racial inequity interfere with the development of the disease. This studyaims to identify the association between social and biological determinants and the occurrence of prostate cancer. This study is a clinical cross-sectional study with 147 men (aged 32 to 94 years old) treated at the Hospital Naval de Salvador (Brazil) for a period of 5 years (2015 to 2020). Sociodemographic data were obtained through semi-structured interviews. Clinical data were collected from medical records, with the following biomarkers: total cholesterol, LDL, HDL and TG. Poisson Regression with Variance was used to estimate PR and 95%CI between outcome and exposure variables(Stata Software, version 12.0). Most patients were men over 61 years old, self-declared black or brown, and with a low level of education. It was observed that men aged over 60 years [PR=1,05; 95%CI= (1,04-1,06) ], with plasma cholesterol > 240 mg/dL [RP: 2.04; 95%CI= (1,03-4,39) ] and who do not use medication [PR=1,31; 95%CI= (1,05-1,63) ] were more likely to have prostate cancer when compared to the reference group. Thus, it is concluded that social and biological factors are relevant for prevention and early detection of the disease and support a better targeting of care, enabling better quality of life.

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