Poder, disputas e geopolítica no setor farmacêutico

João Henrique Santana Stacciarini

doi:10.22481/rg.v8.e2024.e14550

Authors

João Henrique Santana Stacciarini Universidade Estadual de Goiás (UEG) https://orcid.org/0000-0003-3517-9410

DOI:

https://doi.org/10.22481/rg.v8.e2024.e14550

Keywords:

Indústria Farmacêutica, Influência, Economia, Embates, Política

Abstract

The pharmaceutical sector reached global revenues of USD 1.6 trillion in 2023, highlighting its vast economic power and strategic influence on contemporary economics and politics. This article, based on extensive data collection, systematization, and analysis, examines the dynamics of this power and influence. It discusses the economic (and political) value of companies in the sector, the disputes among corporations and nations involved, the geopolitical role played during the COVID-19 pandemic, and the sector's ability to influence domestic policies through intense interaction and financing of legislators, as well as regulatory and oversight agencies.

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Author Biography

João Henrique Santana Stacciarini, Universidade Estadual de Goiás (UEG)

PhD in Geography from the Federal University of Goiás. Post-doctoral fellow, Post-doctoral fellow in the Postgraduate Program in Geography (PPGEO) at the State University of Goiás (UEG).

References

ABRAHAM, John. The pharmaceutical industry as a political player. The Lancet, [S.L.], v. 360, n. 9344, p. 1498-1502, nov. 2002. http://dx.doi.org/10.1016/s0140-6736(02)11477-2.

ACS - American Chemical Society. Emergence of Pharmaceutical Science and Industry: 1870-1930. Chemical & Engineering News. Washington, Estados Unidos, p. 1. 20 jun. 2005. Disponível em: https://cen.acs.org/articles/83/i25/EMERGENCE-PHARMACEUTICAL-SCIENCE-INDUSTRY-1870.html. Acesso em: 22 fev. 2024.

AKHTAR, Gulshan. Indian Pharmaceutical Industry: an overview. Iosr Journal of Humanities and Social Science, [S.L.], v. 13, n. 3, p. 51-66, 2013. http://dx.doi.org/10.9790/0837-1335166.

APOLINÁRIO-JÚNIOR, Laerte et al. Chinese and Indian COVID-19 Vaccine Diplomacy during the Health Emergency Crisis. Revista Brasileira de Política Internacional, [S.L.], v. 65, n. 1, p. 1-24, 2022. http://dx.doi.org/10.1590/0034-7329202200114.

BHARTI, Simant Shankar; BHARTI, Sushant Shankar. India’s Vaccine Diplomacy: role in new order and challenges. Torun International Studies, [S.L.], v. 1, n. 14, p. 93-104, 31 out. 2021. http://dx.doi.org/10.12775/tis.2021.007.

BRANCH, Sarah K.; AGRANAT, Israel. “New Drug” Designations for New Therapeutic Entities: new active substance, new chemical entity, new biological entity, new molecular entity. Journal Of Medicinal Chemistry, [S.L.], v. 57, n. 21, p. 8729-8765, 4 set. 2014. http://dx.doi.org/10.1021/jm402001w.

CASTILHO, Denis. Um vírus com DNA da globalização: o espectro da perversidade. Espaço e Economia, [S.L.], n. 17, p. 1-7, 7 abr. 2020. http://dx.doi.org/10.4000/espacoeconomia.10332.

CHAVEIRO, Eguimar Felício; GONÇALVES, Ricardo Junior de Assis Fernandes. As Margens das Margens das Margens: Saúde do Trabalhador em Tempos de Pandemia da Covid-19. Revista Terceiro Incluído, [S.L.], v. 10, n. 1, p. 227-239, 31 dez. 2020. http://dx.doi.org/10.5216/teri.v10i1.66150.

CITELINE. Pharma Intelligence. Pharma R&D: annual review 2022. Londres (Inglaterra): Pharma Intelligence, 2022. 55 p. Disponível em: https://pharmaintelligence.informa.com/. Acesso em: 23 jan. 2023.

DAMAS, Roberto Dumas. China x EUA: como a economia global e a geopolítica se comportarão no pós-pandemia. São Paulo (Brasil): Saint Paul, 2021. 222 p.

DCB - Daxue Consulting Beijing. China’s pharmaceutical industry will be the world’s largest in less than 10 years. Pequim, China. 2022. 4 p. Disponível em: https://daxueconsulting.com/pharmaceutical-industry-china. Acesso em: 14 fev. 2024.

DIMASI, Joseph A. et al. Innovation in the pharmaceutical industry: new estimates of R&D costs. Journal Of Health Economics, [S.L.], v. 47, p. 20-33, mai. 2016. http://dx.doi.org/10.1016/j.jhealeco.2016.01.012.

DOROCKI, Sławomir. Contemporary Trends in the Development of the Pharmaceutical Industry in the World. Studies of the Industrial Geography Commission of the Polish Geographical Society, [S.L.], v. 25, p. 108-131, 15 jan. 2014. http://dx.doi.org/10.24917/20801653.25.6.

EFPIA - The European Federation of Pharmaceutical Industries and Associations. The Pharmaceutical Industry in Figures. Belgica: EFPIA, 2022. 28 p. Disponível em: https://www.efpia.eu/. Acesso em: 6 fev. 2024.

FACHER, Lev. Pharma funded more than 2,400 state lawmaker campaigns in 2020, new STAT analysis finds. STAT. Boston, EUA. 2021. Disponível em: https://www.statnews.com/feature/prescription-politics/state-full-data-set/. Acesso em: 26 jan. 2024.

FAZAL, Tanisha M.. Health Diplomacy in Pandemical Times. International Organization, [S.L.], v. 74, n. 1, p. 78-97, 16 set. 2020. Cambridge University Press. http://dx.doi.org/10.1017/s0020818320000326.

FORBES. The Global 2000 ranking the world’s largest companies. Jersey City, NJ, EUA: 2023. Disponível em: https://www.forbes.com/lists/global2000/. Acesso em: 10 dez. 2023.

GAUTTAM, Priya et al. COVID-19 and Chinese Global Health Diplomacy: geopolitical opportunity for china’s hegemony?. Millennial Asia, [S.L.], v. 11, n. 3, p. 318-340, 12 out. 2020. http://dx.doi.org/10.1177/0976399620959771.

GCPPP - Global Commission for Post-Pandemic Policy. Covid-19 vaccine production, to July 31st, 2021. GCPPP. 2021. Disponível em: https://globalcommissionforpostpandemicpolicy.org/covid-19-vaccine-production-to-july-31st-2021/. Acesso em: 10 jan. 2024.

GIRÓN, Alicia. Geopolitics and Financial Profitability, the Big Pharmaceutical Corporations. Journal of Economic Issues, [S.L.], v. 56, n. 2, p. 562-569, 3 abr. 2022. http://dx.doi.org/10.1080/00213624.2022.2065853.

GLOBALDATA. Pharma Industry Mergers and Acquisitions Deals by Top Themes in 2022. Londres: (Inglaterra). GlobalData, 2023. 22 p. Disponível em: https://www.globaldata.com/store/report/pharma-industry-m-and-a-deals-by-theme-analysis/. Acesso em: 12 dez. 2023.

HAYES, Michael J.; PRASAD, Vinay. Financial Conflicts of Interest at FDA Drug Advisory Committee Meetings. Hastings Center Report, [S.L.], v. 48, n. 2, p. 10-13, mar. 2018. http://dx.doi.org/10.1002/hast.833.

HIGHAM, Scott; BERNSTEIN, Lenny. The Drug Industry’s Triumph over the DEA. The Washington Post. Washington, Estados Unidos. out. 2017. Disponível em: https://www.washingtonpost.com/graphics/2017/investigations/dea-drug-industry-congress/. Acesso em: 28 dez. 2023.

HORNSEY, Matthew J. et al. Donald Trump and vaccination: the effect of political identity, conspiracist ideation and presidential tweets on vaccine hesitancy. Journal of Experimental Social Psychology, [S.L.], v. 88, p. 103947, mai. 2020. http://dx.doi.org/10.1016/j.jesp.2019.103947.

IBEF - India Brand Equity Foundation. Indian Pharmaceutical Industry. New Delhi, India: Department of Commerce, Ministry of Commerce and Industry, Government of India., 2023. 34 p. Disponível em: https://www.ibef.org/industry/pharmaceutical-india. Acesso em: 9 dez. 2023.

INVEST INDIA - India's national investment facilitation agency. India: Pharmacy to the World. New Delhi, India: Strategic Investment Research Unit (SIRU), 2020. 25 p. Disponível em: https://www.investindia.gov.in/siru/india-pharmacy-world. Acesso em: 9 dez. 2023.

JAKOVLJEVIC, Mihajlo et al. Asian innovation in pharmaceutical and medical device industry - beyond tomorrow. Journal Of Medical Economics, [S.L.], v. 24, n. 1, p. 42-50, 16 nov. 2021. http://dx.doi.org/10.1080/13696998.2021.2013675.

KAMIIKE, Atsuko. The TRIPS Agreement and the Pharmaceutical Industry in India. Journal Of Interdisciplinary Economics, [S.L.], v. 32, n. 1, p. 95-113, 5 dez. 2019. http://dx.doi.org/10.1177/0260107919875573.

KAPCZYNSKI, Amy. The Political Economy of Market Power in Pharmaceuticals. Journal of Health Politics, Policy and Law, [S.L.], v. 48, n. 2, p. 215-239, 27 set. 2022. http://dx.doi.org/10.1215/03616878-10234184

KESSELHEIM, Aaron S. et al. Determinants of Market Exclusivity for Prescription Drugs in the United States. Jama Internal Medicine, [S.L.], v. 177, n. 11, p. 1658, 1 nov. 2017. http://dx.doi.org/10.1001/jamainternmed.2017.4329.

KNIGHT, Victoria et al. Pharma Campaign Cash Delivered to Key Lawmakers with Surgical Precision. KFF Health News. out. 2021. Disponível em: https://kffhealthnews.org/news/article/pharma-campaign-cash-delivered-to-key-lawmakers-with-surgical-precision/. Acesso em: 26 jan. 2024.

LAKDAWALLA, Darius N.. Economics of the Pharmaceutical Industry. Journal of Economic Literature, [S.L.], v. 56, n. 2, p. 397-449, 1 jun. 2018. http://dx.doi.org/10.1257/jel.20161327.

LEE, Seow Ting. Vaccine diplomacy: nation branding and china’s covid-19 soft power play. Place Branding and Public Diplomacy, [S.L.], v. 19, n. 1, p. 64-78, 6 jul. 2021. http://dx.doi.org/10.1057/s41254-021-00224-4.

LIU, Liangtao et al. China’s Vaccine Diplomacy and Its Implications for Global Health Governance. Healthcare, [S.L.], v. 10, n. 7, p. 1276, 10 jul. 2022. http://dx.doi.org/10.3390/healthcare10071276.

LURIE, Peter et al. Financial Conflict of Interest Disclosure and Voting Patterns at Food and Drug Administration Drug Advisory Committee Meetings. JAMA, [S.L.], v. 295, n. 16, p. 1921, 26 abr. 2006. http://dx.doi.org/10.1001/jama.295.16.1921

MCCARTHY, Tom. The race for a vaccine: how Trump's 'America First' approach hinders the global search. The Guardian. Londres (Inglaterra), mai. 2020. Disponível em: https://www.theguardian.com/world/2020/may/12/the-race-for-a-vaccine-how-trumps-america-first-approach-slows-the-global-search. Acesso em: 16 mar. 2024.

MELLO-THÉRY, Neli Ap. de; THÉRY, Hervé. A geopolítica do COVID-19. Espaço e Economia, [S.L.], n. 17, p. 1-9, 7 abr. 2020. OpenEdition. http://dx.doi.org/10.4000/espacoeconomia.11224.

MOHIUDDIN, Muhammad et al. Relocating high-tech industries to emerging markets: case of pharmaceutical industry outsourcing to India. Transnational Corporations Review, [S.L.], v. 9, n. 3, p. 201-217, 3 jul. 2017. http://dx.doi.org/10.1080/19186444.2017.1370808.

MOL, Rajani et al. India’s Health Diplomacy as a Soft Power Tool towards Africa: humanitarian and geopolitical analysis. Journal of Asian and African Studies, [S.L.], v. 57, n. 6, p. 1109-1125, 17 set. 2021. http://dx.doi.org/10.1177/00219096211039539.

NEJSTGAARD, Camilla H et al. Association between conflicts of interest and favourable recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews: systematic review. BMJ, [S.L.], p. 1-12, 9 dez. 2020. http://dx.doi.org/10.1136/bmj.m4234.

NISHINO, Anna et al. The great medicines migration: how china took control of key global pharmaceutical supplies. Nikkei Asia. Tokyo, Japão, p. 1. abr. 2022. Disponível em: https://asia.nikkei.com/static/vdata/infographics/chinavaccine-3/. Acesso em: 12 dez. 2023.

OECD. Health at a Glance 2021: OECD indicators. Paris, França: OECD Publishing, 2021. 274 p. https://doi.org/10.1787/ae3016b9-en.

OPENSECRETS - The nation's premier research group tracking money in U.S. politics. 2023. Washington, Estados Unidos. Disponível em: https://www.opensecrets.org/. Acesso em: 24 abr. 2023.

PAREXEL - International Corporation. The Chinese Pharmaceutical Market: size, r&d, regulations, market access and innovations. Durham, Estados Unidos: Parexel, 2022. 37 p. Disponível em: https://healthadvances.com/whitepaper/health-advances-asia-pacific-pharma.pdf. Acesso em: 11 jun. 2023.

PHAM-KANTER, Genevieve. Revisiting Financial Conflicts of Interest in FDA Advisory Committees. Milbank Quarterly, [S.L.], v. 92, n. 3, p. 446-470, set. 2014. http://dx.doi.org/10.1111/1468-0009.12073.

PINA, Ana Sofia et al. An Historical Overview of Drug Discovery. Ligand-Macromolecular Interactions in Drug Discovery, [S.L.], p. 3-12, 3 out. 2009. http://dx.doi.org/10.1007/978-1-60761-244-5_1.

SALAMON, Lester M.; SIEGFRIED, John J.. Economic Power and Political Influence: the impact of industry structure on public policy. American Political Science Review, [S.L.], v. 71, n. 3, p. 1026-1043, set. 1977. http://dx.doi.org/10.2307/1960105.

SENHORAS, Elói Martins. O Campo de poder das vacinais na Pandemia da Covid-19. Zenodo, [S.L.], v. 18, n. 6, p. 110-121, 22 jun. 2021. http://dx.doi.org/10.5281/ZENODO.5009525.

SHI - The Science History Institute. Alexander Fleming. 2023. Education: Scientific Biographies. Disponível em: https://sciencehistory.org/education/scientific-biographies/alexander-fleming/. Acesso em: 18 dez. 2023.

SOUZA, José Gilberto; GUIMARÃES, Raul. Pandemia de Covid-19: uma análise geopolítica. Saúde e Sociedade, [S.L.], v. 30, n. 1, p. 1-19, 2021. (SciELO). http://dx.doi.org/10.1590/s0104-12902021200649.

STATISTA - Insights and facts across 170 industries and 150 countries. Pharmaceutical market: worldwide revenue 2001-2022. Hamburgo, Alemanha. 2023a. Disponível em: https://www.statista.com/statistics/263102/pharmaceutical-market-worldwide-revenue-since-2001/. Acesso em: 30 nov. 2023.

STATISTA - Insights and facts across 170 industries and 150 countries. Key Players: Pharmaceuticals - Worldwide. Hamburgo, Alemanha. 2023b. Disponível em: https://www.statista.com/outlook/hmo/pharmaceuticals/worldwide#key-players. Acesso em: 14 nov. 2023.

STATISTA - Insights and facts across 170 industries and 150 countries. Pharmaceutical industry in China: statistics & facts. Hamburgo, Alemanha. 2022c. Disponível em: https://www.statista.com/topics/5001/pharmaceutical-industry-in-china/#topicOverview. Acesso em: 15 dez. 2023.

STATISTA - Insights and facts across 170 industries and 150 countries. Top 20 pharmaceutical companies worldwide based on prescription drug market share in 2019 and 2026. Hamburgo, Alemanha. 2022a. Disponível em: https://www.statista.com/outlook/hmo/pharmaceuticals/worldwide#key-players. Acesso em: 14 dez. 2023.

STATISTA - Insights and facts across 170 industries and 150 countries. Total global spending on pharmaceutical research and development from 2014 to 2028. Hamburgo, Alemanha. 2022b. Disponível em: https://www.statista.com/statistics/309466/global-r-and-d-expenditure-for-pharmaceuticals/. Acesso em: 16 dez. 2023.

TANNOURY, Maya; ATTIEH, Zouhair. The Influence of Emerging Markets on the Pharmaceutical Industry. Current Therapeutic Research, [S.L.], v. 86, p. 19 22, 2017. http://dx.doi.org/10.1016/j.curtheres.2017.04.005

TORBATI, Yeganeh; O'CONNELL, Jonathan. Pharmaceutical industry likely to shatter its lobbying record as it works to shape Democrats’ spending bill. The Washington Post. Washington, Estados Unidos. nov. 2021. Disponível em: https://www.washingtonpost.com/business/2021/11/05/pharmaceutical-industry-drug-price-lobbying/. Acesso em: 26 nov. 2023.

WB - World Bank. Data Bank: Gross Domestic Product (GDP). 2023. Disponível em: https://databank.worldbank.org/. Acesso em: 20 nov. 2023.

WOUTERS, Olivier J. Lobbying Expenditures and Campaign Contributions by the Pharmaceutical and Health Product Industry in the United States, 1999-2018. JAMA Internal Medicine, v. 180, n. 5, p. 688, mai. 2020. https://doi.org/10.1001/jamainternmed.2020.0146.

XU, Jian et al. Government subsidies, R&D investment and innovation performance: analysis from pharmaceutical sector in China. Technology Analysis & Strategic Management, v. 33, n. 5, p. 535-553, 9 out. 2020. http://dx.doi.org/10.1080/09537325.2020.1830055.

YU, Peter K. China’s Innovative Turn and the Changing Pharmaceutical Landscape. University of the Pacific Law Review, Stockton, CA, US, v. 3, n. 51, p. 593-620, fev. 2019. Disponível em: https://heinonline.org/HOL/LandingPage?handle=hein.journals/mcglr51&div=38. Acesso em: 12 jun. 2023.

WILKS, Stephen. The Political Power of the Business Corporation. Cheltenham (Reino Unido): Edward Elgar Publishing, 2013. 336 p.